Medicines for root healing (topical and oral)

Vitiligo is a skin disease that often occurs in young people and people with hormonal disorders. To cure the disease, usually the doctor will prescribe topical medication, which can be combined with oral drugs depending on the severity of the disease. Below are the special medicines to treat vitiligo, as well as their dosage and treatment precautions.

Medicines for root healing (topical and oral)

Vitiligo is caused by an invasion of the fungus Pityrosporum ovale, which develops on the surface of the skin, affecting the epidermis, causing changes in skin pigmentation.

As a result of a decrease or loss of pigmentation, the damaged skin may turn lighter or darker than the neighboring skin, usually white, pink or brown. The disease is contagious by nature and is in danger of recurring when in contact with sick people.

To treat vitiligo , usually a doctor will prescribe a number of antifungal drugs that are suitable for you, depending on the location and the condition of the disease. Topical and oral medications that control the symptoms of effective disease are often indicated, including:

1. ASA solution

ASA solution is one of the most effective drugs commonly used for vitiligo. The main ingredients in the solution include: Aspirin, sodium salicylate, ethanol. The drug is prepared in the form of an alcohol solution, usually indicated in such cases:

• Rustic dark disease
• Onychomycosis, fungus of the feet
• Be tall
• Fungal dermatitis

Dosage and administration :

• Before using the drug, the patient should clean the affected skin.
• Use ASA solution applied directly to the skin
• The drug is indicated dosage from 2-3 times / day

Note when using ASA solution :

• Do not use the solution on areas with open wounds.
• Contraindicated in cases with a history of hypersensitivity to any ingredient in the drug.
• During the use of the drug if side effects such as rash, itching, discomfort, local irritation appear. Please discontinue use and contact your doctor for prompt action.
• Avoid using 2 drugs at the same time to minimize drug interactions.

Reference selling price:

• ASA solution has a reference price of about 7,000 VND / bottle

2. The drug Miconazole

Miconazole is a topical medication that causes less side effects. The drug is often indicated for diseases such as:

• Be tall
• Stem fungi, foot fungus, inguinal fungus are caused by fungi T. floccosum, Trichophyton rubrum, T. mentagrophytes.

Dosage and administration :

• The drug is prepared in the form of a gel and cream, and is applied directly to the affected area. Note, before applying the drug should clean the damaged skin.
• For vitiligo apply the drug once a day
• For fungal diseases of the body, foot fungus, inguinal fungus use the drug 2 times a day
• Use drugs to treat vitiligo within 2 weeks, foot fungus should be used within 1 month

If the drug does not go away, you should see your doctor to be examined and adjusted accordingly.

Exercise caution when using the drug :

• Contraindicated to those who are hypersensitive to any of the ingredients in the drug
• For the case of pregnant women, people with porphyria, liver damage should be cautious when using the drug.
• In the process of using the drug can cause some unwanted side effects. Therefore, patients should talk to their doctor before taking the drug.

Reference selling price:

• Miconazole drug has a reference price of about 80,000 VND / tube of 15 grams

3. BSI solution

BSI solution is a topical treatment for vitiligo. The drug contains the main ingredients such as: Benzoic acid, Ethanol, Iodine, Salicylic. Besides treating vitiligo, the drug is also used in the treatment of other dermatological diseases such as hair fungus, onychomycosis, and fungal skin.

How to use the medicine :

• Before using BSI solution, the patient should clean the affected skin to avoid superinfection.
• After wiping dry, apply the medication directly to the area of ​​the skin that is vitiligo.
• Every day apply from 1 to 2 times for the best effect.

In the process of using BSI solution may appear side effects such as :

• Stinging, mild irritation
• Dizziness, headache
• Fast breathing

Caution when using BSI solution :

• Do not use the drug in cases of hypersensitivity to any ingredient of the drug.
• Do not apply medicine to open wounds, mouth, nose, or eyes. If you get drug in these areas, rinse thoroughly with water.
• Avoid applying the drug on sensitive skin, thin skin, note not to apply the drug on a large scale because it may lead to skin irritation.

Reference selling price:

• BSI solution has a reference price of about 10,000 VND / 20ml bottle.

4. Fluconazole medication

Fluconazole oral medicine is effective in the treatment of:

• Diseases caused by mucosal, systemic and skin candidiasis; infection with fungi Histoplasma, Cryptococcus, Blastomyces, Coccidioides.
• Treatment and prevention of fungal infections in people suffering from immune-deficient diseases such as AIDS, organ transplant, pancreas transplant.
• The drug Fluconazole is indicated for cases of vitiligo in severe severity.

Dosage and administration :

Fluconazole is prepared in the form of oral tablets and topical drugs, depending on the severity of the disease and the location that is appropriately prescribed by the doctor.

• In case of vitiligo and other fungal infections of the body, legs, and groin, use 150mg / time / week.
• Candida oropharyngeal infections: Use from 50-100mg / day, use medication for 1 to 2 weeks.
• Vaginal candidiasis: Use 15mg / time, use a single dose.
• For Cryptococcus meningitis: 400mg / day for the first time, 200mg / day for the next times. Use medication within 6 to 8 hours. To prevent recurrence, use 100-200mg / day.

In the process of using the drug can cause some side effects such as :

• Stomachache
• Nausea and vomiting
• Headache
• Diarrhea
• Flatulence
• Urticaria itchy rash

When you notice unusual signs after taking the drug, you should notify the treating doctor so that it can be handled promptly.

Contraindications :

• Hypersensitivity to any of the ingredients in the drug
• The cases are being treated with drugs cisapride, astemizol, pimozide
• Concomitant use of the drug with terfenadine

Reference selling price:

• Fluconazole has a reference price of about 12,000 VND / tablet. The drug has 2 types of boxes: Box of 1 blister x 1 tablet and box of 1 blister x 10 tablets.

5. Clotrimazol ointment

The drug Clotrimazol is a topical medicine for medicinal herbs, Clotrimazol does not apply to those hypersensitive to the ingredients in the drug, people with hypersensitivity to imidazole or topical clotrimazole.

Dosage and administration :

To treat the symptoms of vitiligo and other skin diseases, you use the following medications:

• Clean the damaged skin and dry with a clean towel
• Take a sufficient amount of Clotrimazol and apply thinly to the skin
• Apply topical medication 2 times a day, using the treatment for 2 weeks to bring good results
• Avoid scratching the skin during application

Side effects :

While using Clotrimazol topical treatment for vitiligo can cause some side effects such as:

• The skin is slightly red and stinging
• Itching, blisters
• Urticaria itchy rash
• Burning skin, local irritation

In addition, depending on the location of each person, different problems will arise. At this time, you should stop using the drug and contact your doctor for prompt examination and treatment.

Reference selling price:

• Clotrimazol topical has a reference price of about 12,000 VND / tube 10 grams

6. Itraconazole medicine

The drug is prepared in the form of an oral tablet, which is commonly used to treat vitiligo. Sugar medications are used in some cases such as:

• People with vaginal and vaginal candidiasis
• Fungal infections of the skin, vitiligo, keratitis caused by fungus
• Yeast, onychomycosis caused by dermatophyte
• Oral candidiasis
• Visceral fungus caused by Aspergillus, Candida, Cryptococcus, …

Dosage and administration :

In case of yeast or onychomycosis caused by dermatophyte:

• Interval treatment: Take the drug 2 times / day, each time use 2 pills equivalent to 200mg. Treatment within 7 days. For nail fungus, the drug is used 2 times; Toenail fungus drug 3 times. Each session is about 1-3 weeks apart.
• Continuous treatment: Take 2 capsules per day, use the drug for 3 months.

In case of visceral fungus:

• The dosage of the drug will vary depending on the type of fungal infection.

Note :

• Take medicine after eating.
• Avoid crushing the medication to drink because it can cause side effects, so take the medicine with water.
• Inform your doctor before using the drug for people with kidney failure, liver, children.

Contraindications :

• Hypersensitivity to any ingredients in the drug.
• Women are pregnant and are breast-feeding
• People are being treated with HMG-CoA inhibitors, CYP3A4 metabolites, midazolam and Triazolam.

In the process of using the drug can cause some side effects such as :

• Shortness of breath
• Fever
• Unusual weight gain, swelling
• Tinnitus, problem vision
• Numbness, tingling
• Jaundice
• Loss of bladder control
• Nausea and vomiting
• Anorexia, body weakness
• Rapid heartbeat
• Dark, painful urination when urinating

Symptoms, if not controlled in time, can be life-threatening. Therefore, before using the drug, the patient should consult a specialist doctor. In the course of taking the drug if there are any unusual signs should immediately notify the doctor.

Reference selling price:

• Itraconazole oral drug has a reference price of about 16,000 VND / tablet, box of 2 blisters x 10 tablets.

7. Terbinafin medicine

Terbinafin is an effective treatment for vitiligo and is available in oral and topical form. Assigned to cases of scalp, foot fungus, onychomycosis, Candida on the skin, especially vitiligo.

Based on the patient’s condition and the location of the patient, the doctor will prescribe a reasonable dose of medicine, achieve the best effect.

Usually the drug will be effective after a few days of treatment, the clinical symptoms will improve. If after 2 weeks of taking the medicine there is no sign of improvement, you should actively visit your doctor to be monitored and change the dosage accordingly.

Note when using drugs to treat vitiligo

During the treatment of vitiligo, patients should note the following issues to achieve the best therapeutic effect:

• Use medication as directed by a specialist. Especially for oral drugs, do not add or reduce the dose voluntarily because it can cause unwanted side effects, affecting the treatment results.
• For topical drugs, before using the drug, you should clean the treated skin and hands clean to avoid the risk of superinfection.
• Only use a sufficient amount of medication on the damaged skin, avoid applying the drug on a large scale because it can cause skin irritation.
• After applying the drug, the skin should be well ventilated, avoid bandages because it can cause the amount of medicine absorbed by the body through the skin causing side effects.
• During the use of the drug, if there are any unusual signs, discontinue use and contact a doctor for prompt monitoring and handling.

Above are the oral and topical drugs to treat vitiligo effectively. Medication is for reference only. Therefore, patients should proactively come to the hospital for examination to be prescribed the most suitable treatment, to avoid unfortunate risks.