What does Medrol do? Usage and dosage how?

Medrol is indicated for arthritis, rheumatoid arthritis, atopic dermatitis, bronchial asthma, ulcerative colitis … Clear information about amount, usage, side effects will help patients. Use drugs properly, ensure safety.

• Drug group: Hormones, Hormones
• Dosage form: Tablets
• Packaging: Each box of 2-3 blisters, each blister of 10 tablets.

Information you need to know about Medrol

1. Ingredients

Methylprednisolone…………. 16g

2. What does Medrol do?

Active ingredient Methylprednisolone is a steroid, has anti-inflammatory effect. Used to treat disorders:

Endocrine disorders:

• Patients with primary or secondary adrenocortical insufficiency
• The inflamed thyroid does not produce pus
• Congenital adrenal hyperplasia
• Indicated for the cases of high blood calcium and in the treatment of cancer: Breast cancer, acute leukemia, lymphoma, prostate cancer

Non-endocrine disorders:

• Used for short-term adjuvant therapy for conditions: psoriatic arthritis, rheumatoid arthritis , ankylosing spondylitis, rheumatism, nonspecific acute bursitis, synovitis fluid caused by degenerative joint disease, acute gout arthritis, osteoarthritis core snout, acute and subacute serosa.
• Medrol drugs are indicated in the exacerbation stage or for maintenance treatment in some cases: systemic dermatitis, systemic lupus erythematosus, acute rheumatism, giant cell arteritis low, heart level
• Cases of skin diseases: Herpes bullae dermatitis, pemphigus, atopic dermatitis, exfoliative dermatitis, fungal papilloma, erythema multiforme, severe psoriasis, seborrheic dermatitis heavy body.
• Severe allergies, including anaphylaxis
• Used to control severe allergies, or difficult to treat such as bronchial asthma, allergic rhinitis , serum sickness, contact dermatitis …
• Have primary nephrotic syndrome
• Serious acute or chronic inflammation and allergies in the eyes such as: allergic conjunctivitis, keratitis, sympathetic eye inflammation, neuritis, allergic conjunctivitis …
• Diseases of the digestive tract such as inflammation of the small intestine, ulcerative colitis.
• Hematological disorders such as secondary thrombocytopenia, idiopathic thrombocytopenic purpura in adults, acquired thrombolytic anemia
• Help urinate, reduce protein in nephrotic syndrome.
• Cases of multiple sclerosis, associated with brain tumors
• Respiratory diseases such as: acute or diffuse pulmonary tuberculosis, symptomatic sarcoid, Loeffler syndrome, berylli poisoning …
• Perform an organ transplant
• Meningococcal tuberculosis with subarachnoidal obstruction, helminthiasis involving the heart muscle and nerves.

In addition, Medrol may be ordered in other cases not covered by us. Contact your doctor for more information.

3. Contraindications

• Hypersensitivity to any component of the drug
• Avoid medications for pregnant and lactating women

4. Dosage used

For adults:

Starting dose from 4 – 48mg / day, can be used in single or divided doses.

• Rheumatoid arthritis: The starting dose is 4-6mg / day; use 16 – 32mg / day in acute attacks, then reduce dose quickly.
• Scleroderma disease: Take 160mg / day for 1 week. After that, the dose is reduced to 64mg / time, once every 2 days for 1 month.
• Acute asthma attack: Medrol treatment with a dose of 32 – 48mg / day, the duration of treatment within 5 days. Once the acute attack has passed, drastically reduce the dose.
• For cases of severe rheumatism: Take the drug 0.8mg / kg / day. Divided into small doses, then used a single dose for daily use.
• Having primary nephrotic syndrome: The starting dose is 0.8 – 1.6mg / kg for 6 weeks. Then, reduce the dose and continue treatment for about 6-8 weeks.
• In case of chronic ulcerative colitis: If mild, hold 80mg / day, during severe exacerbations, take Medrol 8 – 24mg / day.
• Having sarcoid: Take 0.8mg / kg / day to help relieve the disease. Then use with a low maintenance dose of 8mg / day.
• Immune hemolytic anemia: Dosage 64mg / day for 3 days. A course dose lasts about 6-8 weeks.

For children:

• Impaired adrenal cortex: Use 0.177mg / kg, divided into 3 doses.
• Treatment of other diseases: 0.417 – 1.67mg / kg, divided into 3-4 times.

5. How to take Medrol

To ensure effective and safe use of the drug, patients need to pay attention to the following:

• Take medication exactly as directed by your doctor. In case of long-term treatment and want to stop the drug, do not stop suddenly but gradually decrease.
• Alternate treatment is possible, which will help patients on long-term medication. Minimize unwanted effects.
• Take Medrol with filtered water, do not chew or crush it but need to take a whole pill. Because crushing the drug can cause the body to absorb too much active ingredient, increasing the risk of side effects.
• Before taking Medrol treatment, be sure to fully inform your doctor about all medications you are taking, including vitamins and herbs.
• If overdose or hypersensitivity reactions are observed in the body, contact the nearest medical facility for prompt emergency care.

6. How to treat the missed dose

If you forget the dose, take it as soon as possible. In the case of preparing until the next dose, skip the old dose. Do not take a double dose in one dose.

7. Storage

Store the drug in a cool, dry place, at a temperature below 30 degrees C. Avoid exposing the drug to sunlight and keep the drug out of the reach of children.

Things to keep in mind when using Medrol

1. Side effects

During treatment with Medrol, patients may experience the following side effects:

• Causes infections, opportunistic infections
• Have cushing syndrome, hypothyroidism, and sudden steroid discontinuation syndrome.
• Body water retention, weight gain, glucose imbalance
• Make the body’s emotions unstable, behave abnormally, in some cases fall into depression, mania, have suicidal intentions.
• Insomnia, irritability, mood fluctuations, psychosis, psychosis, or anxiety, personality changes
• Increases blood sugar-lowering factors in the body, increases metabolism, keeps sodium in the body, increases insulin requirements.
• Cataract, glaucoma, eye bulging, dark retina central serous disease
• Cardiovascular disorders such as high blood pressure, low blood pressure, congestive heart failure
• Abdominal pain, bloating, bloating, diarrhea
• Gastrointestinal ulcers, stomach bleeding, esophagitis, intestinal perforation, nausea, pancreatitis
• Causes joint pain. muscle atrophy, growth retardation, muscle weakness, osteoarthritis
• Skin edema, erythema, petechiae, ecchymosis, pruritus, atrophy of the skin, papular rash
• Causes bone stiffness, fractures, osteoporosis
• May cause complications in people who have been injured, have had surgery or poisoning such as: A compression fracture, causing ligaments to be broken …
• High blood pressure, congestive heart failure, low blood pressure

Depending on the person’s location, Medrol can cause other side effects that are not covered by us. Contact your doctor for more detailed advice on this issue.

2. Drug Interactions

Medrol can alter the pharmacokinetics and properties of other drugs. Therefore, the thing to do is to tell the doctor the medicines you are taking. In particular, the following drugs can interact with Medrol:

• Carbamazepine
• Isoniazid
• Rifampicin
• Neuromuscular blockers
• Forsaprepitant, Aprepitant
• Phenytoin, Phenobarbital
• Antidiabetic drugs
• Cholinesterase enzyme inhibitors
• Troleandomycin
• Ketoconazole, Itraconazole
• Aminogluthimid
• Diltiazem
• Ethinylestradiol/norethindron
• Potassium-lowering drugs
• Cyclosporin
• HIV – protease inhibitors
• Tacrolimus, Cyclophosphamid
• Erythromycin, Clarithromycin
• High dose aspirin
• Cigarette
• Alcohol
• Grapefruit juice …

Above is information you need to know about Medrol. If you still wonder what Medrol does, how to use it and how much to use, you can refer to the information above to find the answer. Taking medicine always has the potential to cause side effects for the user. Therefore, it is important to ensure compliance with the prescription of the doctor throughout the treatment.

Reputable source ThuocLP Vietnamese Health: Medrol: Uses, dosage & usage

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